File:Dna-SNP.svg

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Dna-SNP.svg‎ (SVG file, nominally 416 × 521 pixels, file size: 59 KB)

Contents

[edit] Summary

Description

A Single Nucleotide Polymorphism is a change of a nucleotide at a single base-pair location on DNA. Created using Inkscape v0.45.1.
Date

6 July 2007(2007-07-06)
Source

Own work
Author

David Hall (Gringer)
Permission
(Reusing this image)

See below.

[edit] Construction process

[taken from w:User_talk:Emw2012#Re:_Modeling_DNA.27s_double_helix_in_SVG]

The curve was an attempt at making a sine wave. I did this by making a sawtooth/zigzag line using the grid, converting all the nodes to symmetric, then manually weaking them to look smoother (and chopping off the end bits of the waves to get rid of the straight line mess). More recent versions of Inkscape simplify this process a lot by way of spiro paths and angle snapping.

I created a "band" of DNA by duplicating one curve and shifting right a few spaces, then combining paths and joining the ends with a straight-line segment. Then I added an appropriate fill colour and apply shading. Another band was added by duplicating this one and shifting right an appropriate amount for the major/minor groove. The overlap was carried out by dividing the bands into two (can't recall exactly where, probably at the upper point where they thin out), which allows them to go under at one location and over at another.

For the 3Dish shading, I followed a tutorial I found on the Inkscape website for creating 3D ropes/tubes [1]:

  1. Create a thick curve (say width 10px)
  2. Convert to path
  3. Duplicate
  4. blur (about 3 seems to work well for a 20px line) and lower the duplicate, then shift right and down a bit
  5. Select both original and blurred duplicate, object->clip->set

The bases were generated from thick, cloned lines that had been converted into paths. I tried to match the colours that seem typical for sequencer outputs, and did curves for C/G and points for A/T to indicate differences in hydrogen bonding.

I'm Not sure how pedantic I was about measurements and distances/proportions on that image, but there's a diagram of DNA in Genetics by Russell which gives distances for width of the DNA, distance per turn, number of bases per turn and distance between major/minor groove.

Oh, and I triple checked to make sure I actually had right-handed DNA [2].

[edit] Licensing

I, the copyright holder of this work, hereby publish it under the following licenses:
GNU head Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled "GNU Free Documentation License".

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Creative Commons Attribution Creative Commons Share Alike		 This file is licensed under the Creative Commons Attribution ShareAlike 3.0 License. In short: you are free to share and make derivative works of the file under the conditions that you appropriately attribute it, and that you distribute it only under a license identical to this one. Official license

This licensing tag was added to this file as part of the GFDL licensing update.

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Date/TimeThumbnailDimensionsUserComment
current01:40, 6 July 2007Thumbnail for version as of 01:40, 6 July 2007416×521 (59 KB)Gringer (Talk | contribs) ({{Information |Description=A Single Nucleotide Polymorphism is a change of a nucleotide at a single base-pair location on DNA. Created using Inkscape v0.45.1. [modified to remove long tails on DNA] |Source=self-made |Date=2007-07-06 |Author=David Hall (~~)
00:56, 6 July 2007Thumbnail for version as of 00:56, 6 July 2007471×521 (59 KB)Gringer (Talk | contribs) ({{Information |Description=A Single Nucleotide Polymorphism is a change of a nucleotide at a single base-pair location on DNA. Created using Inkscape v0.45.1. |Source=self-made |Date=2007-07-06 |Author=David Hall (~~~) |other_versions= }})

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