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English: Primidone is an anticonvulsant of the pyrimidinedione class, the active metabolites of which, phenobarbital (major) and phenylethylmalonamide (PEMA) (minor), are also anticonvulsants. It is used mainly to treat complex partial, simple partials, generalized tonic-clonic seizures, myoclonic, akinetic seizures and since the 1980s it has been a valuable alternative to propranolol in the treatment of essential tremor. Unlike other anticonvulsants such as carbamazepine and valproic acid, primidone is rarely used in the treatment of bipolar disorder or any other psychiatric problem. It is also not widely used in treatment of neuropathic pain, trigeminal neuralgia, or migraine. Primidone has been occasionally used to treat long QT syndrome, cerebral palsy, and athetosis.
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Media in category "Primidone"
The following 9 files are in this category, out of 9 total.
- Primidona.gif 256 × 256; 426 KB
- Primidone ball-and-stick.png 2,000 × 1,440; 331 KB
- Primidone metaboliti.PNG 960 × 720; 75 KB
- Primidone Structural Formula V1.svg 226 × 238; 8 KB
- Primidone structure.svg 580 × 643; 9 KB
- Primidone synthesis 1.svg 512 × 139; 35 KB
- Primidone Synthesis.png 2,043 × 588; 16 KB
- Primidone.png 850 × 1,018; 43 KB
- Primidone.svg 512 × 593; 3 KB