File:Clinical characteristics of individuals with MDP syndrome Figure 3.png
Clinical_characteristics_of_individuals_with_MDP_syndrome_Figure_3.png (231 × 364 pixels, file size: 172 KB, MIME type: image/png)
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DescriptionClinical characteristics of individuals with MDP syndrome Figure 3.png |
English: Picrosirius red staining of abdominal subcutaneous adipose tissue from subject 1 (upper image) and a representative comparative image of a BMI-matched subject (lower image). Scale bars, 500 μm. Adipose tissue from subject 1 with a POLD1 mutation shows a considerable amount of fibrosis (red staining). |
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Date | |||
Source | An in-frame deletion at the polymerase active site of POLD1 causes a multisystem disorder with lipodystrophy, Nature Genetics 45, 947–950 (2013) doi:10.1038/ng.2670 | ||
Author | Michael N Weedon, Sian Ellard, Marc J Prindle, Richard Caswell, Hana Lango Allen, Richard Oram, Koumudi Godbole, Chittaranjan S Yajnik, Paolo Sbraccia, Giuseppe Novelli, Peter Turnpenny, Emma McCann, Kim Jee Goh, Yukai Wang, Jonathan Fulford, Laura J McCulloch, David B Savage, Stephen O'Rahilly, Katarina Kos, Lawrence A Loeb, Robert K Semple & Andrew T Hattersley | ||
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