File:DwMRI FDG PET and histology in sCJD.tif
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DescriptionDwMRI FDG PET and histology in sCJD.tif |
English: (a) Axial diffusion‑weighted magnetic resonance imaging and apparent diffusion coefficient map, demonstrating increase in cortical signal on
the diffusion‑weighted sequence and corresponding decrease in apparent diffusion coefficient. This is cortical diffusion restriction. (b) Images from the 18fluoro‑deoxy‑glucose component of the positron emission tomography/computed tomography: An axial section at the level of the basal ganglia and a coronal section including the cerebellum. Both show heterogeneous marked reduction in cerebral cortical metabolism. 18Fluoro‑deoxy‑glucose uptake in cerebellar cortex is preserved (normally less avid than cerebral cortex). There is some more subtle hypometabolism affecting the left basal ganglia and thalamus. (c) Photomicrographs of sections of occipital cortex, the upper is stained with hematoxylin and eosin, and the lower with KG9 antibody following proteinase treatment. 20 μm scale bar. They show spongiform change in the striate cortex and proteinase resistant prion deposits |
Date | |
Source | http://www.wjnm.org/text.asp?2021/20/4/411/328210 |
Author | World Journal of Nuclear Medicine |
Morley NC, Hofer M, Wilkinson P, Bradley KM. 18FDG PET-CT in sporadic Creutzfeldt-Jakob disease, correlated with MRI and histology. World J Nucl Med [serial online] 2021 [cited 2021 Nov 25];20:411-3. Available from: http://www.wjnm.org/text.asp?2021/20/4/411/328210 archive copy at the Wayback Machine
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current | 10:28, 25 November 2021 | 1,426 × 892 (3.64 MB) | Ncdm22 (talk | contribs) | Uploaded a work by World Journal of Nuclear Medicine from http://www.wjnm.org/text.asp?2021/20/4/411/328210 with UploadWizard |
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