File:From-Principle-to-Practice-Bridging-the-Gap-in-Patient-Profiling-pone.0054728.s004.ogv

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Original file(Ogg multiplexed audio/video file, Theora/Vorbis, length 16 s, 1,066 × 718 pixels, 472 kbps overall)

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Description
English: The effect of factor VIII product half-life on the dynamics of thrombin generation over time post administration of fVIII. Each unit of time (spanning 1900–1921) in the video represents 8 hours. Thrombin generating capacity was simulated by inputting a single subject's (H1 from Figure 4) factor levels into our mathematical model. The theoretical fVIII products used here have half-lives of 6, 12.2, 18 and 24 hours. By definition the 6 hour product decays much faster than products with longer half-lives and therefore the thrombin generating capacity of the 6 hour product declines fastest followed by the 12.2, 18 and 24 hour products.
Date
Source Movie S4 from Foley J, Orfeo T, Undas A, McLean K, Bernstein I, Rivard G, Mann K, Everse S, Brummel-Ziedins K (2013). "From Principle to Practice: Bridging the Gap in Patient Profiling". PLOS ONE. DOI:10.1371/journal.pone.0054728. PMID 23372761. PMC: 3556038.
Author Foley J, Orfeo T, Undas A, McLean K, Bernstein I, Rivard G, Mann K, Everse S, Brummel-Ziedins K
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current02:33, 12 February 201316 s, 1,066 × 718 (929 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.
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