File:Hiventrytocell.jpg
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This file has been superseded by HIV entry into T cell schematic.png. It is recommended to use the other file. Please note that deleting superseded images requires consent. Reason to use the other file: "A PNG version of this file is now available."
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| Description |
"Schematic Representation of the Key Structural Features of SIV and HIV-1 Entry into T Cells (A) Different stages of viral entry from budding, to maturation, to entry claw formation. For the SIV strain used here, viruses that are docked to the cell via an entry claw show very few, if any, viral spikes on their surface, whereas non-contacting viruses typically display between 60 and 100 spikes on their surface. The entry claw is composed of between five to seven anchors spanning the region between the virus and the cell, each ∼100 Å long, and spaced laterally by ∼150 Å. (B and C) Two alternative models for viral entry. In the global fusion model (B), the formation of the entry claw is followed by progressive fusion of the viral membrane across its width, leading to merger of the contents of the viral membrane with the cellular membrane. In the local fusion model (C), the formation of the entry claw is followed by the creation of a local pore centered at one of the rods, leading to delivery of the viral core into the cell." |
| Date | Published May 4, 2007 |
| Source |
From: Electron Tomography of the Contact between T Cells and SIV/HIV-1: Implications for Viral Entry Sougrat R, Bartesaghi A, Lifson JD, Bennett AE, Bess JW, et al. PLoS Pathogens Vol. 3, No. 5, e63 doi:10.1371/journal.ppat.0030063 Available at [1] |
| Author | Rachid Sougrat, Alberto Bartesaghi, Jeffrey D. Lifson, Adam E. Bennett, Julian W. Bess, Daniel J. Zabransky, Sriram Subramaniam |
| Permission (Reusing this file) |
PLoS |
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  This file is licensed under the Creative Commons Attribution 2.5 Generic license.
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 This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 18:23, 11 September 2007 | | 2,805 × 3,405 (466 KB) | Calliopejen (talk | contribs) | {{Information |Description="(A) Different stages of viral entry from budding, to maturation, to entry claw formation. For the SIV strain used here, viruses that are docked to the cell via an entry claw show very few, if any, viral spikes on their surface, |
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