File:Immunogenetic-Mechanisms-Driving-Norovirus-GII.4-Antigenic-Variation-ppat.1002705.g011.jpg

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Immunogenetic-Mechanisms-Driving-Norovirus-GII.4-Antigenic-Variation-ppat.1002705.g011.jpg ‎(643 × 488 pixels, file size: 82 KB, MIME type: image/jpeg)

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English: PGM binding blockade activity against GII.4.1987 (Panel A) and GII.4.2006 (Panel C) Epitope A–E chimeric VLPs. Sigmoidal curves were fit to the mean percent control binding calculated by comparing the amount of VLP bound to PGM in the presence of antibody pretreatment to the amount of VLP bound in the absence of antibody pretreatment. Error bars represent the standard error of the mean. Mean EC50 (% plasma) for blockade of each GII.4.1987 (Panel B) and GII.4.2006 (Panel D) epitope-exchanged VLP. * VLPs with EC50 values significantly different from the EC50 for each parental VLP.
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Source Image file from Lindesmith L, Beltramello M, Donaldson E, Corti D, Swanstrom J, Debbink K, Lanzavecchia A, Baric R (2012). "Immunogenetic Mechanisms Driving Norovirus GII.4 Antigenic Variation". PLOS Pathogens. DOI:10.1371/journal.ppat.1002705. PMID 22615565. PMC: 3355092.
Author Lindesmith L, Beltramello M, Donaldson E, Corti D, Swanstrom J, Debbink K, Lanzavecchia A, Baric R
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current21:43, 4 January 2016Thumbnail for version as of 21:43, 4 January 2016643 × 488 (82 KB)Recitation-bot (talk | contribs)Automatic upload of media from: doi:10.1371/journal.ppat.1002705

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