File:Sessile serrated adenoma 2 high mag.jpg

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English: High magnification micrograph of a sessile serrated adenoma, abbreviated SSA, from the cecum removed during a colonoscopy. H&E stain.

SSAs are characterized by:

  • basal dilation of the crypts,
  • basal crypt serration,
  • crypts that run horizontal to the basement membrane (horizontal crypts), and
  • crypt branching.

Unlike traditional colonic adenomas (e.g. tubular adenoma, villous adenoma), they do not typically have nuclear changes (nuclear hyperchromatism, nuclear crowding, elliptical/cigar-shaped nuclei).

SSAs are considered pre-malignant lesions, i.e. precursors to cancer, and tend to be found in the right colon.

Related images

Another case:

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Author Nephron


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current05:18, 16 July 2010Thumbnail for version as of 05:18, 16 July 20102,848 × 4,272 (5.4 MB)Nephron (talk | contribs){{Information |Description={{en|1=High magnification micrograph of a '''sessile serrated adenoma''', abbreviated '''SSA''', from the cecum removed during a colonoscopy. [[w:H&E
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