File:“Mini-brains” generated from PSCs.webp
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“Mini-brains” generated from PSCs
Summary[edit]
| Description |
English: “Mini-brains” representative of different brain region identities were generated in Yan Liu’s laboratory. a Immunofluorescence image of cortical organoids grown from pluripotent stem cells (PSCs) with multiple rosette-like structures. Shown are immunohistochemical staining images for the adherens junction marker PKCλ (green), the progenitor marker SOX2 (red) and the proliferative marker KI67 (green) after 30 days of differentiation. b Immunofluorescence of the midbrain dopamine (DA) neuron marker TH (green), the floor plate progenitor marker FOXA2 (red) and PKCλ (green) at 50 days in midbrain organoids. c Image of striatal organoids stained for the medium spiny neuron (MSN) marker DARPP32 (green) and the mature neuron marker NEUN (green). d Staining for KI67 (green) and SOX2 (red) in cerebellar organoids at 30 days. Scale bar, 100 μm |
| Date | |
| Source | https://www.nature.com/articles/s41392-022-01024-9/figures/4 |
| Author | Xiao-Yan Tang, Shanshan Wu, Da Wang, Chu Chu, Yuan Hong, Mengdan Tao, Hao Hu, Min Xu, Xing Guo & Yan Liu |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 12:27, 7 September 2023 | | 1,971 × 465 (276 KB) | DoctorNaturopath (talk | contribs) | Uploaded a work by Xiao-Yan Tang, Shanshan Wu, Da Wang, Chu Chu, Yuan Hong, Mengdan Tao, Hao Hu, Min Xu, Xing Guo & Yan Liu from https://www.nature.com/articles/s41392-022-01024-9/figures/4 with UploadWizard |
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