File:508 2020 1763 Fig3 HTML.webp

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Captions

Captions

Structural organization of coronavirus particle and the spike protein S.

Summary[edit]

Description
English: Structural organization of coronavirus particle and the spike protein S. a Schematic of virus particle. b Ribbon diagrams of the soluble S protein trimer. The three monomers are colored in red, gold, and grey. In the closed state, the receptor-binding domain (RBD) is in the ‘down’ conformation (protein data bank: PDB 6ZGI, [95]), and in the open state in the ‘up’ conformation (protein data bank: PDB 6ZGG, [95]), which can interact with the viral receptor ACE2 (angiotensin-converting enzyme 2). The interaction site is indicated by a blue ellipse in the right panel
Date
Source Heinz, F.X., Stiasny, K. Profile of SARS-CoV-2. Wien Klin Wochenschr 132, 635–644 (2020). https://doi.org/10.1007/s00508-020-01763-1
Author Franz X. Heinz and Karin Stiasny

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