File:Acantholytic squamous carcinoma (52048888894).jpg

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Acantholytic squamous carcinoma, also known as adenoid, pseudoglandular or pseudovascular SCC, has been reported most frequently in the skin and appears to be rare in the lungs. It is characterized by loss of cohesion between tumor cells due to loss of adhesion molecules at desmosomes that may result in gland-like and vascular-like structures that may be misinterpreted as adenocarcinoma or angiosarcoma respectively. These tumors consistently express squamous markers such as p40 and p63 which are used to confirm the diagnosis.

Images contributed by Dr. Rola Ali - @DrRolaAli
Date
Source Acantholytic squamous carcinoma
Author Atlas of Pulmonary Pathology from USA

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This image was originally posted to Flickr by Dr. Y Rosen at https://flickr.com/photos/30950973@N03/52048888894. It was reviewed on 12 October 2022 by FlickreviewR 2 and was confirmed to be licensed under the terms of the cc-by-sa-2.0.

12 October 2022

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current18:39, 12 October 2022Thumbnail for version as of 18:39, 12 October 2022941 × 642 (403 KB)Netha Hussain (talk | contribs)Transferred from Flickr via #flickr2commons

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