File:Botulinum A1 6DKK.png
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Summary[edit]
DescriptionBotulinum A1 6DKK.png |
English: Botulinum toxin A1 (BoNT/A1). PDB: 3BTA. Botulinum toxins always consist of 2 peptide chains: light and heavy.
Light chain (green) binds a zinc ion (red) as a cofactor. Light chain is linked to heavy chain's N-terminal "belt" by a disulfide bond (yellow, -S-S-). Heavy chain (H) has 3 parts:
Naturally occurring botulinum toxins are always combined with their corresponding non-toxic non-hemagglutinin (NTNHA or NTNH) into a minimally functional progenitor toxin complex (M-PTC). NTNHA is not in this crystal structure. Sources:
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Author | 5-HT2AR |
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