File:Classic Invasive Lobular Carcinoma of the Breast, Signet Ring Cells (6959258351).jpg

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This tumor included a tiny proportion of signet-ring cells. These can be very "signety" and fool you into seeking a gastric primary that does not exist. I have even seen such a case present primarily as a signet ring cell carcinoma of the endometrium on a D&C specimen. It took quite a while and not a few phone calls to get to the bottom of that!

Pathological and histological images courtesy of Ed Uthman at flickr.
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Classic Invasive Lobular Carcinoma of the Breast, Signet Ring Cells

Author Ed Uthman from Houston, TX, USA

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This image, originally posted to Flickr, was reviewed on 11 December 2013 by the administrator or reviewer File Upload Bot (Magnus Manske), who confirmed that it was available on Flickr under the stated license on that date.

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