File:Lax 33014 elife-33014-fig7-v1.jpg
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English: Intron/intein encoded endonuclease-mediated interference completion between related viruses.
(1) Two related viruses infect the same host cell. The green virus genome contains a selfish element encoding a homing endonuclease. (2) During initial replication, the endonuclease is expressed and cleaves the unoccupied locus on the yellow virus’ genome impairing its replication. (3) Due to suppressing its competitor’s replication, the majority of the viral progeny is of the green virus’ type. (4) The yellow virus can rescue its genome by using the green virus’ genome as a template. This creates a chimeric genome containing the selfish element and the endonuclease as well as adjacent sequences originating from the green virus’ genome. |
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| Source |
Fig. 7 at https://elifesciences.org/articles/33014/figures at https://elifesciences.org/articles/33014 The kinetoplastid-infecting Bodo saltans virus (BsV), a window into the most abundant giant viruses in the sea. In: eLife 2018;7:e33014 doi:10.7554/eLife.33014  |
| Author | Christoph M. Deeg, Cheryl-Emiliane T. Chow, Curtis A. Suttle |
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