File:The four views of systems biology.png

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English: Four different types of networks used to represent biological processes and their features are shown. a ∣ An interaction network can be used to represent physical interactions (black line) — such as that between extracellular signal-regulated kinase (ERK) and ELK1 — and functional interactions (grey lines), such as those between UBC9 (also known as UBE2I), ERK, ELK1 and c-FOS. b ∣ An activity flow can be used to show the stimulation of c-FOS activity by ELK1 activity, the stimulation of ELK1 activity by ERK activity, and its inhibition by UBC9 activity. c ∣ A detailed process description can be used to show the catalysis of ELK1 sumoylation (SUMO) and phosphorylation (P), their reversed reactions, and the trigger of c-FOS expression. The graph is simplified by the inexistence of ELK1 with both covalent modifications. d ∣ Entity relationships can be used to describe the stimulation of sumoylation and phosphorylation of ELK1 by UBC9 and ERK, respectively, and the influence of these processes on c-FOS.
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current12:22, 3 May 2018Thumbnail for version as of 12:22, 3 May 20182,266 × 1,657 (404 KB)Lenov~commonswiki (talk | contribs)User created page with UploadWizard

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