File:Wound healing phases.svg

Summary[edit]

DescriptionWound healing phases.svg	English: Phases of wound healing. Limits vary within faded intervals, mainly by wound severity.
Date	25 September 2010
Source	Own work (from the template Logarithmic time scale - milliseconds to years.svg)
Author	Mikael Häggström
Other versions

References[edit]

Inflammation and maturation and remodeling:

• worldwidewounds.com > Figure 3 - The time relationship between the different processes of wound healing. by Gregory S Schultz, Glenn Ladwig and Annette Wysocki - in turn adapted from Asmussen PD, Sollner B. Mechanism of wound healing. In: Wound Care. Tutorial Medical Series. Stuttgart: Hippokrates Verlag, 1993.

Vasoconstriction and vasodilation:

• Stadelmann W.K., Digenis A.G. and Tobin G.R. (1998). Physiology and healing dynamics of chronic cutaneous wounds. The American Journal of Surgery 176 (2): 26S-38S. PMID 9777970 Hamilton, Ont. B.C. Decker, Inc. Electronic book

Angiogenesis:

• Nguyen, D.T., Orgill D.P., Murphy G.F. (2009). Chapter 4: The Pathophysiologic Basis for Wound Healing and Cutaneous Regeneration. Biomaterials For Treating Skin Loss. CRC Press (US) & Woodhead Publishing (UK/Europe), Boca Raton/Cambridge, p. 25-57. (ISBN 978-1-4200-9989-9 Invalid ISBN, ISBN 978-1-84569-363-3)

Polymorphonuclear neutrophils and fibroplasia and granulation tissue formation:

• de la Torre J., Sholar A. (2006). Wound healing: Chronic wounds. Emedicine.com. Accessed January 20, 2008. http://www.emedicine.com/plastic/topic477.htm

Macrophages:

• Expert Reviews in Molecular Medicine. (2003). The phases of cutaneous wound healing. 5: 1. Cambridge University Press. Accessed January 20, 2008. http://www-ermm.cbcu.cam.ac.uk/03005829a.pdf

Fibroblast proliferation and migration

• Stadelmann W.K., Digenis A.G. and Tobin G.R. (1998). Physiology and healing dynamics of chronic cutaneous wounds. The American Journal of Surgery 176 (2): 26S-38S. PMID 9777970 Hamilton, Ont. B.C. Decker, Inc. Electronic book

Collagen deposition, epithelialization and contraction:

• Romo T. and Pearson J.M. 2005. Wound Healing, Skin. Emedicine.com. Accessed December 27, 2006.

Additional note on contraction:

• Mulvaney M. and Harrington A. 1994. Chapter 7: Cutaneous trauma and its treatment. In, Textbook of Military Medicine: Military Dermatology. Office of the Surgeon General, Department of the Army. Virtual Naval Hospital Project. Accessed through web archive on September 15, 2007. https://web.archive.org/web/20031218072356/http://www.vnh.org/MilitaryDerm/Ch7.pdf

Percentage of normal tissue strength:

• Mercandetti M., Cohen A.J. (2005). Wound Healing: Healing and Repair. Emedicine.com. Accessed January 20, 2008. http://www.emedicine.com/plastic/topic411.htm

Upper limit of angiogenesis:

• "Some months" given in: Page 550 (section Angiogenesis, Macrophages, and Remodeling) in: William D. Figg (2008) Angiogenesis an integrative approach from science to medicine, Berlin: Springer ISBN: 0-387-71517-7. [1]

Licensing[edit]

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