File:Autosomal-Recessive-Transmission-of-a-Rare-KRT74-Variant-Causes-Hair-and-Nail-Ectodermal-Dysplasia-pone.0093607.g002.jpg
Autosomal-Recessive-Transmission-of-a-Rare-KRT74-Variant-Causes-Hair-and-Nail-Ectodermal-Dysplasia-pone.0093607.g002.jpg (734 × 310 pixels, file size: 69 KB, MIME type: image/jpeg)
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DescriptionAutosomal-Recessive-Transmission-of-a-Rare-KRT74-Variant-Causes-Hair-and-Nail-Ectodermal-Dysplasia-pone.0093607.g002.jpg |
English: (A) Clustal Omega alignment of part of Keratin-74 shows complete evolutionary conservation of the Phe274 residue (shaded) in all species with a known keratin-74 ortholog. (B) Alignment of parts of the 26 human type II keratins illustrating the almost identical homology at amino-acid position 274 (shaded). Only Keratin-80 deviates by having a biochemically similar leucine at this position. Position of the first amino acid shown is indicated to the left of each protein sequence. KRT: Keratin. |
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Source | Image file from Raykova D, Klar J, Azhar A, Khan T, Malik N, Iqbal M, Tariq M, Baig S, Dahl N (2014). "Autosomal Recessive Transmission of a Rare KRT74 Variant Causes Hair and Nail Ectodermal Dysplasia: Allelism with Dominant Woolly Hair/Hypotrichosis". PLOS ONE. DOI:10.1371/journal.pone.0093607. PMID 24714551. PMC: 3979697. | |
Author | Raykova D, Klar J, Azhar A, Khan T, Malik N, Iqbal M, Tariq M, Baig S, Dahl N | |
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current | 20:35, 8 January 2016 | 734 × 310 (69 KB) | Recitation-bot (talk | contribs) | Automatic upload of media from: doi:10.1371/journal.pone.0093607 |
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Publisher | Public Library of Science |
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Source | info:doi/10.1371/journal.pone.0093607 |
Date(s) | 8 April 2014 |
Identifier | info:doi/info:doi/10.1371/journal.pone.0093607.g002 |
IIM version | 2 |