File:Collected papers (1904) (14591483200).jpg

Identifier: p1collectedpaper07list (find matches)
Title: Collected papers
Year: 1904 (1900s)
Authors: Lister Institute of Preventive Medicine, London
Subjects: Medicine
Publisher: London
Contributing Library: Gerstein - University of Toronto
Digitizing Sponsor: University of Toronto

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ion for the following reasons. In the first place,some workers of great reputation never employ for diagnostic purposes mixtures containing anappreciable number of clumps, say more than two or three per cent. In the second place, tlieexclusion of clumps would tend arbitrarily to heighten the proportion of cells cont^iining 0 bacilli,since cells containing clumps must be regarded as possessing a phagocytic power at lea«t equalto those which contain one bacillus apiece; indeed, Harvey and McKendrick have adducedevidence t which supports a belief that it is rather the number of bacteria than the number ofacts of ingestion which should be taken as a measure of phagocytic power. * 1428 cells with 0 bacilli per cell will occur not in 20,000, hut in 20,360; hence in 20.000 we shallhave not 1428 but 1402-75, the excess is distributed proportionally among the other groups : see p. oiV.i.t Biometrika, Vol. vii. p. 64. .08 On the Distribution of the Means of Samples TABLE 11. 350 8000 2500 2000
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I ISOO 6 1 6^ 0 10 Number of Bacilli.Graph 1. Curve of 20,000 cells. Constants of Fitted Curve. , = 2-6031, ^, = 1-0365, /3. = 4-2622, .,= -1-6752, . = 22-8160, ^ = 41f58 .-. = «:.,. 10-4354 «. = 2-7r;61, a, = 38-7997, ,yo = 3478-81, SkewneHS = -6069 Mode at 21000,Mian at 3-6;97, Start of curve ^t - 6562, End at 408996, x^ = 86-2, P very small, / X V-380C/ X Y^^ I M. Greenwood and J. D. C. White 509 Recognising the force of this objection, it was decided to examine the effect of inchidingclumps in the count. To this end, another 2000 cells were counted on the slides already usedand clumped cells were included. Of the 2000 cells counted in this way 36, or TB \>er cent.,contained clumi)ed bacteria. Now if we allow, as seems reasonable, that this latter enumerationwas a fair sample of the population, then the frequencies in our 20,000 cells would be changedin the manner shown in the second column of Table I, We have distributed the clumped cellsamong the other fre(iuencies above zer

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