File:Free-Fatty-Acid-Induced-PP2A-Hyperactivity-Selectively-Impairs-Hepatic-Insulin-Action-on-Glucose-pone.0027424.g005.jpg

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Free-Fatty-Acid-Induced-PP2A-Hyperactivity-Selectively-Impairs-Hepatic-Insulin-Action-on-Glucose-pone.0027424.g005.jpg ‎(418 × 308 pixels, file size: 51 KB, MIME type: image/jpeg)

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English: Cantharidin (Can) (a) or Okadaic acid (OA) (b) inhibition of PP2A resulted in an increased Ser473 phosphorylation of Akt in palmitate-treated hepatocytes stimulated with 10 nM insulin. Fold change is relative to no Cantharidin or Okadaic acid. Akt phosphorylation levels of were normalized to the total amounts of Akt. Data are averages of western blot quantifications +/− std. error of the mean, n = 8. * indicates p<0.05 vs. no Cantharidin or Okadaic acid. Representative western blots are shown.
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Source Image file from Galbo T, Olsen G, Quistorff B, Nishimura E (2011). "Free Fatty Acid-Induced PP2A Hyperactivity Selectively Impairs Hepatic Insulin Action on Glucose Metabolism". PLOS ONE. DOI:10.1371/journal.pone.0027424. PMID 22087313. PMC: 3210172.
Author Galbo T, Olsen G, Quistorff B, Nishimura E
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current22:41, 7 May 2016Thumbnail for version as of 22:41, 7 May 2016418 × 308 (51 KB)Recitation-bot (talk | contribs)Automatic upload of media from: doi:10.1371/journal.pone.0027424

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