File:Mouse embryo Pre-macrophages infiltrate embryonic tissues.jpg
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| Description | Fig 2. Pre-macrophages infiltrate embryonic tissues. a Isolated E10.5 Cx3cr1GFP/+ embryo. b, c Visualization (b) and quantification (c) of CX3CR1+ macrophages in different embryonic regions at indicated time points; * p < 0.05 (one-way ANOVA with Tukey’s multiple comparisons test: head vs. trunk p = 0.0107, head vs. tail p = 0.0121, trunk vs. tail p = 0.9860); graph shows median ± IQR. d Quantification by flow cytometry of CX3CR1 GFP+ cells in the embryonic YS, brain and trunk at indicated time points; (**) p = 0.0017 (two-tailed Mann–Whitney test); median ± IQR. e CX3CR1 GFP+ cells (green) in the embryonic brain at E16.5 additionally stained for the endothelial marker CD31 (red). f Image series extracted from live E10.5 video sequences (Supplementary Movie 6) show a cell attaching to the endothelium in the embryonic head region; direction of flow from top to bottom. Scale bars are 1 mm (a), 100 µm (b, e, f) |
| Date | |
| Source | https://www.nature.com/articles/s41467-017-02492-2/figures/2 Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun 9, 75 (2018). https://doi.org/10.1038/s41467-017-02492-2 |
| Author | Stremmel, C., Schuchert, R., Wagner, F. et al. |
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| current | 20:25, 21 April 2024 | | 1,346 × 2,383 (2.14 MB) | Rasbak (talk | contribs) | {{Information |description=Fig 2. Pre-macrophages infiltrate embryonic tissues. a Isolated E10.5 Cx3cr1>sup>GFP/+</sup> embryo. b, c Visualization (b) and quantification (c) of CX<sub>3</sub>CR1+ macrophages in different embryonic regions at indicated time points; * p < 0.05 (one-way ANOVA with Tukey’s multiple comparisons test: head vs. trunk p = 0.0107, head vs. tail p = 0.0121, trunk vs. tail p = 0.9860); graph shows median ± IQR. d Quantification by flow cytometry of CX<sub>3</sub>CR1 GFP... |
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