Jean Comandon, pioneer of microcinematography (time-lapse microscopy), recorded this time-lapse video at the Pasteur Institute in c. 1910, using an ultramicroscope. The video show living syphilisspirochaetes moving among red blood cells of frog. Note the back-and-forth movement, characterizing disease-causing spirochaete. The video is believed to be the oldest preserved time-lapse microscopy video.
