File:説明図 酵素 酸塩基触媒部位.png

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説明図_酵素_酸塩基触媒部位.png(445 × 312 pixels, file size: 48 KB, MIME type: image/png)

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日本語: 説明図 酵素 酸塩基触媒部位

PDBデータベースより酵素ja:キモトリプシンPDBファイルをDeepViewでイメージ化する。MS Paintでpng化。

Copyright by あら金 2007.

ja:酵素#酵素の内の酸塩基触媒部位より

キモトリプシンなどでは以下のプロトンの伝達のモデルが考えられている。

①His57 がプロトンを負に荷電した Asp102 に譲渡する
②His57 が塩基となり、活性中心の Ser195 からプロトンを奪う
③Ser195 が活性化されて(負に荷電して)基質を攻撃する
(4)His57 がプロトンを基質に譲渡する
(5)Asp102 から His57 がプロトンを奪い ① の状態に戻る

出典

PDB

4VGC
descriptor : GAMMA CHYMOTRYPSIN, D-1-NAPHTHYL-2-ACETAMIDO-ETHANE BORONIC ACID
title : GAMMA-CHYMOTRYPSIN D-NAPHTHYL-1-ACETAMIDO BORONIC ACID INHIBITOR COMPLEX
authors : Stoll, V.S., Eger, B.T., Hynes, R.C., Martichonok, V., Jones, J.B., Pai, E.F.,
exp.method : X-RAY DIFFRACTION
deposition date : 1997-05-01
release date : 1997-11-12
Date
Source Own work
Author あら金

Licensing[edit]

w:en:Creative Commons
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Date/TimeThumbnailDimensionsUserComment
current06:04, 14 January 2007Thumbnail for version as of 06:04, 14 January 2007445 × 312 (48 KB)あら金 (talk | contribs)説明図 酵素 酸塩基触媒部位 PDBデータベースより酵素キモトリプシンPDBファイルを[http://www.expasy.org/spdbv/ DeepView]でイメージ化する。MS Paintでpng化。 {{GFDL}} Copyright by あら金 2007. [[酵�

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