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Rebecca M. Davidson, Nabeeh A. Hasan, Vinicius Calado Nogueira de Moura, Rafael Silva Duarte, Mary Jackson, Michael Strong (2013) Phylogenomics of Brazilian epidemic isolates of Mycobacterium abscessus subsp. bolletii. reveals relationships of global outbreak strains. Infection, Genetics and Evolution <a href="https://dx.doi.org/10.1016/j.meegid.2013.09.012" rel="nofollow">dx.doi.org/10.1016/j.meegid.2013.09.012</a> Published by Elsevier Fig. 1.Phylogenomic relationships of Brazilian epidemic isolates and globally diverse MAB strains. (A) Neighbor-joining phylogeny generated from 27,598 variable genome-wide SNP sites identified in all Mycobacterium abscessus (MAB) strains compared to the M. abscessus subsp. abscessus (MAB-A) ATCC 19977 complete reference genome. The tree supports the previously recognized subspecies as monophyletic groups. (B) A clade composed almost entirely of M. abscessus subsp. bolletii (MAB-B) epidemic or outbreak strains is distinguished by 76 SNPs; among these only a single SNP distinguished the BRA-100 strains CRM-0019 and CRM-0020 from the UK CF-related and Malaysian M18 strains. GO-06 is the basal most member of this clade and is most-closely related to the most recent common ancestor of the MAB-B outbreak strains. |
Date | |
Source | 1-s2.0-S1567134813003535-gr1 |
Author | Phylogeny Figures |
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