File:13311 2018 674 Fig2 HTML.webp
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[edit]Description13311 2018 674 Fig2 HTML.webp |
English: Molecular genetics of mitochondrial myopathy. A search of OMIM, ClinVar, and Mitomap from genes causing mitochondrial myopathy yielded 60 genes. Of these, 31 are mitochondrial genes, including 8 protein-encoding and 23 tRNA mutations. The remaining 29 genes are encoded by the nucleus and have a variety of functions, including subunits and assembly factors of the respiratory chain, mtDNA replication and maintenance, mitochondrial shape, mitochondrial translation, transport, proteases, lipid metabolism, and iron sulphur (Fe-S) cluster formation. Due to the speed at which needed genes are identified, this is likely to be an underestimate of causative genes. |
Date | |
Source | https://link.springer.com/article/10.1007/s13311-018-00674-4 |
Author | Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent |
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current | 21:21, 13 April 2024 | 685 × 520 (66 KB) | Ozzie10aaaa (talk | contribs) | Uploaded a work by Syeda T. Ahmed, Lyndsey Craven, Oliver M. Russell, Doug M. Turnbull & Amy E. Vincent from https://link.springer.com/article/10.1007/s13311-018-00674-4 with UploadWizard |
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2018
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2fc5136ac361115ccf35277b091e220aaca2ee4a
67,118 byte
520 pixel
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