File:5-Figure2-1.png

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file(956 × 714 pixels, file size: 370 KB, MIME type: image/png)

Captions

Captions

Crofelemer

Summary

[edit]
Description
English: Figure 2 Mechanisms involved in the development of secretory diarrhea.

Notes: The CFTR and CaCC are responsible for the secretion of chloride ions into the intestinal lumen. Secretory diarrhea develops due to hyperactivity of these channels. Crofelemer binds to the CFTR and CaCC and inhibits chloride secretion, thus halting secretory diarrhea. Abbreviations: Ca2+ , calcium; CaCC, calcium-activated chloride channels; cAMP, cyclic adenosine monophosphate; CFTR, cystic fibrosis transmembrane conductance regulator; Cl– , chloride; H2 O, water; K+ , potassium; Na+

, sodium; NKCC, sodium potassium chloride cotransporter.
Date
Source https://www.dovepress.com/getfile.php?fileID=16766
Author Twisha S Patel ,Rustin D Crutchley ,Anne M Tucker, Jessica Cottreau, Kevin W Garey

Licensing

[edit]
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current20:00, 13 December 2023Thumbnail for version as of 20:00, 13 December 2023956 × 714 (370 KB)Ozzie10aaaa (talk | contribs)Uploaded a work by Twisha S Patel ,Rustin D Crutchley ,Anne M Tucker, Jessica Cottreau, Kevin W Garey from https://www.dovepress.com/getfile.php?fileID=16766 with UploadWizard

There are no pages that use this file.