File:Bronquiolo terminal E-Clara G-Cilia.png

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Español: Figura 2. Falta de marcadores selectivos de células ciliadas y de Clara después de la deleción de Sox2 .

En ratones de cuatro semanas de edad, la tinción con hematoxilina y eosina del control de las secciones de pulmón demostraron:
un epitelio cuboide a escamoso bajo anormal en los bronquiolos grandes (A) y los bronquiolos pequeños (C).
La tinción inmunohistoquímica demostró la pérdida de CCSP (Scgb1a1) un marcador de células de Clara (E), marcadores de células ciliadas α-tubulina (G).
Las flechas indican las regiones que se muestran en los recuadros.

La barra de escala es de 50 µm, la barra de escala de los recuadros es de 10 µm.
Date
Source Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells. PLoS ONE 4(12): e8248. doi:10.1371/journal.pone.0008248
Author Tompkins D.H., Besnard V., Lange A.W., Wert S.E., Keiser A.R., Smith A.N., Lang R., Whitsett J.A. (2009)

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