File:Canine piroplasmosis Plate IX Nuttall 1905 14 15.jpg

English: Piroplasma canis in the blood of dogs. Plate IX from: (1905). "Canine Piroplasmosis. II". The Journal of Hygiene 5 (3): 237-249.. Figure numbers have been added for clarity.

Piroplasma canis in the blood of dogs experimentally infected in Cambridge with the South African disease. The dogs were infected by ticks and by blood inoculations. Stained by Leishman's method. Drawn with Zeiss Apochr. 1/12 oil immersion objective and eyepiece 12, larger than they were seen because of the impossibility of reproducing the details in smaller figures. The figures in the Plate consequently all appear magnified about 3400. Drawn by G. H. F. N. Figs. 1 — 8. Young intracorpuscular forms, rings, and dividing ovoid bodies ending in a group of four. Blood obtained chiefly from the peripheral circulation, also from spleen and lung smears. Figs. 9 — 32. Series of intracorpuscular parasites beginning with a large single oval parasite. Longitudinal fission leading to groups of typical pyriform bodies etc., in groups of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 21. The nuclear division is seen to precede the separation of the daughter cells. Figs. 9 and 10 from liver and spleen smears; 12 — 15, from peripheral blood, the rest chiefly from spleen, bone- marrow, lung, and liver smears. Figs. 33 — 42. Amoeboid forms in spleen and marrow smears. Fig. 43. Large amoeboid form in peripheral blood. Fig. 44. Large spherical form with exceptionally large chromatin masses. Developing sexual form? (brain). Fig. 45. Nucleated red corpuscle containing two parasites. Fig. 4G. Group of 10 free parasites liberated from a corpuscle of which all trace has dis- appeared (lung). Figs. 47 — 58. Parasites in various stages of development and lying free in the plasma (lung and spleen). Figs. 59—62. Sausage-shaped gametes (?) lying free in the plasma in peripheral blood. Figs. 63 — 67. Infected corpuscles taken up by leucocytes and undergoing progressive degeneration in order of the figures from left to right. lu Fig. 67 only the chromatin

masses of the parasites are left.