File:Differentiation Neural Progenitors.jpg

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English: Title: Directed Differentiation Of Multipotential Human Neural Progenitor Cells

Description: Human neural progenitor cells were isolated under selective culture conditions from the developing human brain and directed through lineage differentiation to GFAP + (glial fibrillary acid protein) astrocytes. Following 3 weeks in astrocyte selective medium, cells were fixed and stained with antibodies to intermediate filament proteins that characterize the cells as either astrocytes (GFAP in orange) or neural progenitor cells (nestin in green). Nuclei are stained with DAPI in blue. Microscopic examination over the course of differentiation showed loss of progenitor cells (nestin down regulation) as cell population increasingly became astrocytes (GFAP up regulation). Photomicrograph was taken on Axiovert 200M Zeiss inverted microscope at 200 x magnification. Categories: Research in NIH Labs and Clinics Type: Color, Photo Source: National Institute of Neurological Disorders and Stroke (NINDS) Creator: Carol N. Ibe And Eugene O. Major Date Created: Unknown Date Added: 5/24/2012

Reuse Restrictions: None - This image is in the public domain and can be freely reused. Please credit the source and/or author listed above.
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Source National Institutes of Health (NIH)
Author National Institutes of Health (NIH)

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This work is in the public domain in the United States because it is a work prepared by an officer or employee of the United States Government as part of that person’s official duties under the terms of Title 17, Chapter 1, Section 105 of the US Code. Note: This only applies to original works of the Federal Government and not to the work of any individual U.S. state, territory, commonwealth, county, municipality, or any other subdivision. This template also does not apply to postage stamp designs published by the United States Postal Service since 1978. (See § 313.6(C)(1) of Compendium of U.S. Copyright Office Practices). It also does not apply to certain US coins; see The US Mint Terms of Use.

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