File:Mecanisme d'acció dels mimètics de BH3.png
Mecanisme_d'acció_dels_mimètics_de_BH3.png (720 × 441 pixels, file size: 90 KB, MIME type: image/png)
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[edit]DescriptionMecanisme d'acció dels mimètics de BH3.png |
Català: Quan es pren un mimètic de BH3 com a fàrmac, aquest forma un complex amb les proteïnes antiapoptòtiques BH1-4 i impedeix que aquestes inhibeixin a les proteïnes proapoptòtiques de la seva família (per exemple, Bak i Bax). Això resulta en la via intrínseca de l'apoptosi, on es forma un porus mitocondrial mitjançant les proteïnes Bak i Bax i surt el citocrom C del mitocondri donant com a resultat final la mort cel·lular de les cèl·lules canceroses. |
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Source | Own work |
Author | BCP24 TobajaP |
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current | 20:44, 6 May 2024 | ![]() | 720 × 441 (90 KB) | BCP24 TobajaP (talk | contribs) | Uploaded own work with UploadWizard |
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Vertical resolution | 28.34 dpc |