File:PGK1 activity in glycolysis and regulation by acetylation.jpg

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search

Original file ‎(850 × 769 pixels, file size: 726 KB, MIME type: image/jpeg)

Captions

Captions

Add a one-line explanation of what this file represents

Summary

[edit]
Description PGK1 activity in glycolysis and regulation by acetylation. PGK1 function is regulated by acetylation at K323, which enhances PGK1 enzymatic activity, improves glycolytic metabolism and promotes tumor growth. K323 acetylation is regulated by PCAF and SIRT7, allowing stimulation or inhibition of PGK1 function. P300/CBP-associated factor (PCAF) is a transcriptional coactivator associated with p53 promoting acetylation of PGK1. Conversely, NAD-dependent deacetylase sirtuin 7 (SIRT7), a nuclear enzyme, suppressed DNA recombination. GAPDH: glyceraldehyde 3 phosphate dehydrogenase. PGK1: Phosphoglycerate kinase 1
Date
Source https://www.researchgate.net/publication/331706360_Resistance_to_anoikis_in_transcoelomic_shedding_The_role_of_glycolytic_enzymes Resistance to anoikis in transcoelomic shedding: The role of glycolytic enzymes. Pleura and Peritoneum. 4. 10.1515/pp-2019-0003.
Author Wilson, Robert & Solass, Wiebke & Archid, Rami & Weinreich, Jürgen & Königsrainer, Alfred & Reymond, Marc.
This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.

Licensing

[edit]
w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current14:16, 3 June 2024Thumbnail for version as of 14:16, 3 June 2024850 × 769 (726 KB)Rasbak (talk | contribs){{Information |description=PGK1 activity in glycolysis and regulation by acetylation. PGK1 function is regulated by acetylation at K323, which enhances PGK1 enzymatic activity, improves glycolytic metabolism and promotes tumor growth. K323 acetylation is regulated by PCAF and SIRT7, allowing stimulation or inhibition of PGK1 function. P300/CBP-associated factor (PCAF) is a transcriptional coactivator associated with p53 promoting acetylation of PGK1. Conversely, NAD-dependent deacetylase sirt...

You cannot overwrite this file.

There are no pages that use this file.

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:PGK1_activity_in_glycolysis_and_regulation_by_acetylation.jpg&oldid=881111618"