File:PegUricase.png
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DescriptionPegUricase.png |
English: A comparison of uricase (pdb:1uox) and PEG-uricase (model). PEG-uricase includes 40 polymers of 10kDa PEG. PEGylation improves its solubility at physiological pH, increases serum half-life and reduces immunogenicity without compromising activity. Upper images show the whole tetramer, lower images show an example of one of the lysines that is PEGylated. (PEG-uricase model from reference[1], only 36 PEG polymers included) |
Date | |
Source | Own work |
Author | Evolution and evolvability |
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 23:50, 21 February 2015 | 2,192 × 2,136 (1.65 MB) | Evolution and evolvability (talk | contribs) | User created page with UploadWizard |
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22 February 2015
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