File:Pharmaceuticals-15-00048-g001.jpg

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Pharmaceuticals-15-00048-g001.jpg ‎(743 × 552 pixels, file size: 112 KB, MIME type: image/jpeg)

Captions

Captions

Deucravacitinib

Summary

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Description
English: Alternate mechanisms of JAK inhibition. Deucravacitinib inhibits TYK2 activation by interacting with the pseudokinase (JH2) domain (allosteric inhibition), while first-generation jakinibs inhibit enzymatic activity by binding to the ATP-binding (JH1) domain (competitive inhibition).
Date
Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779366/
Author Madison Alexander, Yiming Luo, Giorgio Raimondi, John J. O’Shea, and Massimo Gadina

Licensing

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attribution
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current21:08, 20 December 2023Thumbnail for version as of 21:08, 20 December 2023743 × 552 (112 KB)Ozzie10aaaa (talk | contribs)Uploaded a work by Madison Alexander, Yiming Luo, Giorgio Raimondi, John J. O’Shea, and Massimo Gadina from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8779366/ with UploadWizard

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