File:Regulació de l'activació de l'AMPK.png
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[edit]DescriptionRegulació de l'activació de l'AMPK.png |
English: El complex LKB1-STRAD-MO25 fosforila AMPK de manera contínua. En absència de senyals de baixa energia, les fosfatases proteiques desfosforilen AMPK. L'estrès energètic afavoreix la unió d'ADP/AMP sobre l'ATP a la subunitat γ, provocant un canvi conformacional que augmenta la fosforilació dependent de LKB1-STRAD-MO25 i disminueix la susceptibilitat a la desfosforilació dependent de fosfatases proteiques.
L'AMPK activat llavors exerceix el seu control sobre el metabolisme mitjançant la fosforilació de molts substrats aigües avall, resultant en la restauració de l'homeòstasi energètica. |
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Source | Own work |
Author | BCP24 GrabuledaJ |
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current | 15:15, 30 April 2024 | 1,736 × 1,210 (321 KB) | BCP24 GrabuledaJ (talk | contribs) | Uploaded own work with UploadWizard |
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