File:Regulatory sequence in a promoter at a transcription start site with a paused RNA polymerase and a TOP2B-induced DNA double-strand break.jpg

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A number of signal-regulated genes that need rapid response times utilize this type of mechanism to initiate transcription of their messenger RNA.

Summary[edit]

Description
English: DNA repair enzymes are bound along withTOP2B at the genomic regulatory sequence location that can respond to signal-timulation with rapid occurrence of a double-strand break. TOP2B, PARP-1, DNA-PKcs, and KU86 and KU70 can all be closely associated with a responsive promoter. These proteins can all be present simultaneously on a single promoter nucleosome (there are about 147 nucleotides in the DNA sequence wrapped around a single nucleosome).
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Author Bernstein0275

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current20:32, 15 April 2021Thumbnail for version as of 20:32, 15 April 20212,204 × 1,303 (910 KB)Bernstein0275 (talk | contribs)Uploaded own work with UploadWizard

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