File:Rosai-Dorfman Disease in Elderly Female - Aziz Et Al Case Rep Pathol 2012.jpg
Rosai-Dorfman_Disease_in_Elderly_Female_-_Aziz_Et_Al_Case_Rep_Pathol_2012.jpg (714 × 446 pixels, file size: 158 KB, MIME type: image/jpeg)
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Summary[edit]
DescriptionRosai-Dorfman Disease in Elderly Female - Aziz Et Al Case Rep Pathol 2012.jpg |
English: The image is a composite of cropped excerpts of https://www.hindawi.com/journals/cripa/2012/806130/fig1/ ("Figure 1: Enlarged right cervical lymph node, 2 x 1.5 cm") on the left and https://www.hindawi.com/journals/cripa/2012/806130/fig3/ ("Figure 3: Many large histiocytes with binucleation and emperipolesis, (FNAC, H&E 400)") on the right. The brightness and contrast of the included images were adjusted to best display the macroscopic and microscopic aspects of Rosai-Dorfman disease.
Accompanying text includes: "A 50-year-old Indian female presented with complaints of low grade intermittent fever off and on, weakness, and slowly enlarging painless nodules in the right side of her neck and right groin for the last one and half years. ... Clinical examination revealed average built, mild pallor along with generalized lymphadenopathy involving right cervical (2 x 1.5 cm, multiple, matted) (Figure 1), right axillary (1 x 1 cm), and right inguinal (2 x 2.5 cm) lymph nodes. ... Fine needle aspiration cytology (FNAC) from the enlarged lymph nodes as well as the chest wall lump revealed inflammatory infiltrate consisting of lymphocytes, plasma cells, sparse population of neutrophils along with multiple large histiocytes with abundant eosinophilic cytoplasm and vesicular nuclei, some showing binucleation. Many of these histiocytes showed emperipolesis (i.e., engulfment of intact lymphocytes and plasma cells). No malignant cells or granuloma were seen (Figure 3). These findings were consistent with the diagnosis of Rosai-Dorfman disease." |
Date | |
Source |
Aziz M, Ray PS, Haider N, Rathore SP. Diagnosis of Rosai-Dorfman Disease in Elderly Female on Fine Needle Aspiration Cytology: A Case Report. Case Rep Pathol. 2012;2012:806130. doi: 10.1155/2012/806130. At https://www.hindawi.com/journals/cripa/2012/806130/. The Web page states "This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited." The link provided is to https://creativecommons.org/licenses/by/3.0/ ("Attribution 3.0 Unported (CC BY 3.0)"). |
Author | Meher Aziz, Prasenjit Sen Ray, Nazima Haider, and Sumit Prakash Rathore. The authors were with the Department of Pathology, J.N. Medical College, AMU, Aligarh 202002, India. |
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Number of components | 3 |
Horizontal resolution | 300 dpi |
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Software used | Adobe Photoshop CS5 Macintosh |
File change date and time | 06:59, 20 September 2017 |
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Unique ID of original document | B870902A72FA4E68EBA83B7AEC8D07A3 |
Date and time of digitizing | 23:34, 19 September 2017 |
Date metadata was last modified | 23:59, 19 September 2017 |