File:SBTS2.png
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| Description |
English: Generic diagram of the sub-domains of Sleeping Beauty transposase.
The 360-amino acid polypeptide has three major subdomains: the amino-terminal DNA-recognition domain that is responsible for binding to the DR sequences in the mirrored IR/DR sequences of the transposon, a nuclear localization sequence (NLS), and a DDE domain that catalyzes the cut-and-paste set of reactions that comprise transposition. The DNA-recognition domain has two paired box sequences that can bind to DNA and are related to various motifs found on some transcription factors; the two paired boxes are labeled PAI and RED. The catalytic domain has the hallmark DDE (sometimes DDD) amino acids that are found in many transposase and recombinase enzymes. In addition, there is a region that is highly enriched in glycine (G) amino acids. |
| Date | |
| Source | Own work |
| Author | Perryhackett |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 19:32, 4 March 2019 | | 720 × 240 (37 KB) | Artoria2e5 (talk | contribs) | move caption to text |
| 21:31, 9 May 2011 |  | 720 × 540 (82 KB) | Perryhackett (talk | contribs) | {{Information |Description ={{en|1=Generic diagram of the sub-domains of Sleeping Beauty transposase.}} |Source ={{own}} |Author =Perryhackett |Date =2011-05-09 |Permission =not needed |other_versions |
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