File:Sequential model of helitron transposition.png
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DescriptionSequential model of helitron transposition.png |
English: Donor sequence (black) and target sequence (blue) ; helitron divided into three parts (LTS in blue, coding sequnce in grey and RTS in purple). a) tyrosine of the Rep-Hel protein cleaves 5’ end of the LTS in the donor sequence ; b) using helicase activity from 5’ to 3’, Rep-Hel rolls to the 3’ end of the RTS ; c) cleavage of the 3’ end after detection of the RTS ; d) joining of the end sequences and formation of circle intermediate ; e) cleavage of the target strand and integration of the helitron after passive resolution |
Date | |
Source | https://www.nature.com/articles/ncomms10716 |
Author | Ivana Grabundzija, Simon A. Messing, Jainy Thomas, Rachel L. Cosby, Ilija Bilic, Csaba Miskey, Andreas Gogol-Döring, Vladimir Kapitonov, Tanja Diem, Anna Dalda, Jerzy Jurka, Ellen J. Pritham, Fred Dyda, Zsuzsanna Izsvák & Zoltán Ivics |
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