File:Toronto General Hospital, Toronto, Ontario (30003269095).jpg

The Toronto General Hospital (TGH) is a major teaching hospital in Toronto, Ontario, Canada, and a part of University Health Network (UHN). It is located in the Discovery District of Downtown Toronto along a portion of University Avenue known as "Hospital Row"; it is directly north of The Hospital for Sick Children, across Gerrard Street West, and east of Princess Margaret Cancer Centre and Mount Sinai Hospital. The hospital serves as a teaching hospital for the University of Toronto Faculty of Medicine. In 2019, Newsweek ranked TGH as seventh among the top-ten best hospitals in the world. In 2017, the hospital was ranked 1st for research in Canada by Research Infosource.

The emergency department now treats 28,065 persons each year, while the hospital also houses the major transplantation service for Ontario, performing heart, lung, kidney, liver, pancreas, and small intestine, amongst others, for patients referred from all over Canada. The hospital is the largest organ transplant center in North America, performing 639 transplants in 2017. The hospital is also renowned for cardiac and thoracic surgery. The world's first single and double lung transplants were performed at TGH in 1983 and 1986 and the world's first valve-sparing aortic root replacement was done by Tirone David at Toronto General Hospital in 1992. In 2015, surgeons performed the world's first triple organ transplant (lung, liver and pancreas) in 19 year old Reid Wylie at Toronto General Hospital. TGH teaches resident physicians, nurses, and technicians; it also conducts research through the Toronto General Research Institute.

Currently, Sophie, Countess of Wessex, as a member of the Canadian Royal Family, is patron of the hospital.

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