File:Viral mediated delivery of genes to neurons 2.jpg
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English: Figure 2.Lentivirus (upper panel) – Part of the retroviridae family (viral sizes are 80-100 nm diameter) derived from HIV-1 virus. To produce lentiviruses with the gene of interest as the lentiviral DNA construct, first transfect cells with a packaging plasmid and the envelope vector (VSVG).
Adeno Associated Virus (AAV) (lower panel) – Member of the parvoviridae family (20 nm diameter). To produce AAV, package a gene of interest into the AAV-ITR vector and transfect cells with a Helper vector and the Rep/Cap DNA integration vector. |
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| Source | http://neuroscience.openetext.utoronto.ca/chapter/3-6-viral-mediated-delivery-of-genes-to-neurons/ |
| Author | University of Toronto |
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