File:Estimating-Dose-Painting-Effects-in-Radiotherapy-A-Mathematical-Model-pone.0089380.s011.ogv

English: Time evolution of a heterogeneous tumor growth (where CCs and CSCs are present) for the low migration case with and CSC cycle duration equal to 96 h. Tumor growth is allowed unchecked from a size of about 105 cells until about 106 cells are present. Then, a homogeneous radiation therapy consisting of 1.30 Gy in the tumor is delivered. Treatment sessions are scheduled along 3 weeks, 5 days a week separated by 12 hours intervals except for weekends, where a 72 hours interval is allowed. Depicted in dark and light green (respectively, dark and light red) are proliferating and quiescent CCs (respectively, proliferating and quiescent CSCs). Dead cells are represented in black. See Figure 11 (E) in the article.