File:Increased-Vulnerability-of-Human-Ventricle-to-Re-entrant-Excitation-in-hERG-linked-Variant-1-Short-pcbi.1002313.s002.ogv
Increased-Vulnerability-of-Human-Ventricle-to-Re-entrant-Excitation-in-hERG-linked-Variant-1-Short-pcbi.1002313.s002.ogv (Ogg Theora video file, length 17 s, 511 × 316 pixels, 508 kbps, file size: 1.01 MB)
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DescriptionIncreased-Vulnerability-of-Human-Ventricle-to-Re-entrant-Excitation-in-hERG-linked-Variant-1-Short-pcbi.1002313.s002.ogv |
English: N588K reentry in idealised 2D geometry. Initiation and conduction of re-entry in a 2D idealised model of the transmural ventricle under the N588K (SQT1 mutant) condition. A planar conditioning wave generated by an S1 stimulus at the ENDO end propagates towards the EPI end. An S2 stimulus is applied to the EPI part during the vulnerable window of the local tissue at 226 ms, which develops into a spiral wave. The spiral wave persists under the SQT1 condition. |
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Source | Video S2 from Adeniran I, McPate M, Witchel H, Hancox J, Zhang H (2011). "Increased Vulnerability of Human Ventricle to Re-entrant Excitation in hERG-linked Variant 1 Short QT Syndrome". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1002313. PMID 22194679. PMC: 3240585. | ||
Author | Adeniran I, McPate M, Witchel H, Hancox J, Zhang H | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 17:00, 30 October 2012 | 17 s, 511 × 316 (1.01 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Adeniran I, McPate M, Witchel H, Hancox J, Zhang H |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | N588K reentry in idealised 2D geometry. Initiation and conduction of re-entry in a 2D idealised model of the transmural ventricle under the N588K (SQT1 mutant) condition. A planar conditioning wave generated by an S1 stimulus at the ENDO end propagates towards the EPI end. An S2 stimulus is applied to the EPI part during the vulnerable window of the local tissue at 226 ms, which develops into a spiral wave. The spiral wave persists under the SQT1 condition. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2011-12 |