File:Pyrazoleamide-compounds-are-potent-antimalarials-that-target-Na+-homeostasis-in-intraerythrocytic-ncomms6521-s3.ogv

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Pyrazoleamide-compounds-are-potent-antimalarials-that-target-Na+-homeostasis-in-intraerythrocytic-ncomms6521-s3.ogv ‎(Ogg Theora video file, length 23 s, 452 × 452 pixels, 481 kbps, file size: 1.3 MB)

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English: Supplementary Movie 1 Live videography of parasitized RBC exposed to 10 nM PA21A050. This video depicts two parasites continuously imaged for 2700 min. There appears to be some progression of the parasites but also apparent swelling. Dramatic morphological changes followed by the bursting of the parasites are apparent between 1500 to 1800 min for the parasite at 4 o'clock position, and between 2400 to 2600 min for the parasite at 11 o'clock position.
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Source Video file from Vaidya A, Morrisey J, Zhang Z, Das S, Daly T, Otto T, Spillman N, Wyvratt M, Siegl P, Marfurt J, Wirjanata G, Sebayang B, Price R, Chatterjee A, Nagle A, Stasiak M, Charman S, Angulo-Barturen I, Ferrer S, Belén Jiménez-Díaz M, Martínez M, Gamo F, Avery V, Ruecker A, Delves M, Kirk K, Berriman M, Kortagere S, Burrows J, Fan E, Bergman L (2014). "Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum". Nature Communications. DOI:10.1038/ncomms6521. PMID 25422853. PMC: 4263321.
Author Vaidya A, Morrisey J, Zhang Z, Das S, Daly T, Otto T, Spillman N, Wyvratt M, Siegl P, Marfurt J, Wirjanata G, Sebayang B, Price R, Chatterjee A, Nagle A, Stasiak M, Charman S, Angulo-Barturen I, Ferrer S, Belén Jiménez-Díaz M, Martínez M, Gamo F, Avery V, Ruecker A, Delves M, Kirk K, Berriman M, Kortagere S, Burrows J, Fan E, Bergman L
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current05:18, 2 November 201623 s, 452 × 452 (1.3 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 118 kbps Completed 12:15, 16 October 2018 7.0 s
Streaming 360p (VP9) Not ready Unknown status
VP9 240P 62 kbps Completed 12:15, 16 October 2018 4.0 s
Streaming 240p (VP9) 62 kbps Completed 03:23, 16 December 2023 1.0 s
WebM 360P 512 kbps Completed 05:18, 2 November 2016 7.0 s
Streaming 144p (MJPEG) 205 kbps Completed 21:20, 20 November 2023 1.0 s

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