File:Spontaneous-restoration-of-transplantation-tolerance-after-acute-rejection-ncomms8566-s2.ogv

English: Supplementary Movie 1 Spontaneous acceptance of a second donor-matched abdominal allograft next to the rejected first allograft by infected tolerant recipients. A first BALB/c heart was transplanted in the peritoneal cavity of a B6 recipient treated with anti-CD154 + DST resulting in transplantation tolerance. Infection with Lm i.p. on day 60 post-transplantation resulted in acute rejection of the first graft 1 week later. A second B/c heart was transplanted immediately below the first rejected allograft 3 weeks after Lm infection, in the absence of immunosuppression. The video was taken at sacrifice, 60 days after second transplantation, and shows the first non-beating white fibrotic allograft (white arrow) and the fully vascularized beating second donor-matched allograft (red arrow).