File:A-Drosophila-Model-for-EGFR-Ras-and-PI3K-Dependent-Human-Glioma-pgen.1000374.s017.ogv
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[edit]DescriptionA-Drosophila-Model-for-EGFR-Ras-and-PI3K-Dependent-Human-Glioma-pgen.1000374.s017.ogv |
English: An animated 27 µm thick confocal z-stack of dEGFRλ; dp110CAAX tumor cells derived from transplanted larval glia, pictured in Figure 3F. The depth of each frame is noted in the upper left-hand corner. 20 µm scale bar for x/y-axis. Transplanted mutant glia are labeled with membrane bound CD8GFP (green) and the Repo nuclear protein (blue). Actin staining (red, phalloidin) reveals abdominal anatomy of the host. Arrowheads in indicate dEGFRλ;dp110CAAX glial cells invading an ovary, distinguished by its characteristic actin staining (bright red). An asterisk indicates trachea embedded in this dEGFRλ;dp110CAAX tumor, visible as a hollow actin-positive (red) tubule running through the tissue. Genotypes: Hosts were w1118 virgin females. Transplanted glia were UAS-dEGFRλ UAS-dp110CAAX/+; UAS-CD8GFP/+; repo-Gal4/+. |
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Source | Video S2 from Read R, Cavenee W, Furnari F, Thomas J (2009). "A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma". PLOS Genetics. DOI:10.1371/journal.pgen.1000374. PMID 19214224. PMC: 2636203. | ||
Author | Read R, Cavenee W, Furnari F, Thomas J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:57, 16 November 2012 | 2.4 s, 760 × 970 (1.51 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Read R, Cavenee W, Furnari F, Thomas J |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009-02 |
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