File:A-Sensitized-Screen-for-Genes-Promoting-Invadopodia-Function-In-Vivo-CDC-42-and-Rab-GDI-1-Direct-pgen.1005786.s013.ogv

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A-Sensitized-Screen-for-Genes-Promoting-Invadopodia-Function-In-Vivo-CDC-42-and-Rab-GDI-1-Direct-pgen.1005786.s013.ogv ‎(Ogg multiplexed audio/video file, Theora/Vorbis, length 3.6 s, 456 × 352 pixels, 356 kbps overall, file size: 157 KB)

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English: The invadopodial membrane is mis-trafficked after loss of the vulval precursor cells. A 3D reconstruction of a lateral view time-lapse of a lin-3 RNAi treated AC visualizing the invadopodial membrane component PI(4,5)P2 (cyan; cdh-3>mCherry::PLCδPH) and the basement membrane (magenta; lam-1>lam-1::GFP).). lin-3 RNAi treatment results in loss of the vulval precursor cells, which inhibits generation of the vulval cue. Loss of the vulval precursor cells resulted in mis-trafficking of the invadopodial membrane to the lateral and apical plasma membrane. The time-lapse takes place over a 40-minute period. The images were acquired in one-minute intervals using a spinning disc confocal microscope (CSU-10; Yokogawa Electric Corporation). The frames are played at 10 frames per second. This video corresponds to Fig 6C. Sclae bar, 5 μm.
Date
Source S7 Movie from Lohmer L, Clay M, Naegeli K, Chi Q, Ziel J, Hagedorn E, Park J, Jayadev R, Sherwood D (2016). "A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation". PLOS Genetics. DOI:10.1371/journal.pgen.1005786. PMID 26765257. PMC: 4713207.
Author Lohmer L, Clay M, Naegeli K, Chi Q, Ziel J, Hagedorn E, Park J, Jayadev R, Sherwood D
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Date/TimeThumbnailDimensionsUserComment
current05:16, 29 January 20163.6 s, 456 × 352 (157 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 240P 80 kbps Completed 22:11, 15 August 2018 2.0 s
Streaming 240p (VP9) 77 kbps Completed 05:49, 9 December 2023 1.0 s
WebM 360P 459 kbps Completed 13:05, 16 November 2023 1.0 s
Streaming 144p (MJPEG) 613 kbps Completed 09:01, 29 October 2023 1.0 s
Stereo (Opus) 5 kbps Completed 20:25, 12 November 2023 1.0 s
Stereo (MP3) 130 kbps Completed 01:18, 29 October 2023 1.0 s

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