File:Active and Inactive AMPK.tif

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Active_and_Inactive_AMPK.tif ‎(720 × 415 pixels, file size: 879 KB, MIME type: image/tiff)

Captions

Captions

Active adenosine monophosphate-activated protein kinase (AMPK, left) and inactive AMPK (right)

Summary[edit]

Description
English: Active adenosine monophosphate-activated protein kinase (AMPK, left) and inactive AMPK (right). AMPK is a protein complex composed of three subunits: α (green), β (brown), and γ (blue). When bound to adenosine monophosphate (AMP), AMPK is activated and the active loop is protected against phosphatases. When bound to adenosine triphosphate (ATP), AMPK undergoes a large conformational change wherein part of the α subunit associates weakly with the γ subunit ~100Å away, the active loop is exposed to phosphatases, and AMPK is deactivated.
Date
Source Own work
Author Lbattist

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Date/TimeThumbnailDimensionsUserComment
current17:00, 10 May 2022Thumbnail for version as of 17:00, 10 May 2022720 × 415 (879 KB)Lbattist (talk | contribs)Uploaded own work with UploadWizard

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