File:An example of a lysibody.jpg
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[edit]DescriptionAn example of a lysibody.jpg |
English: A. The binding domain from a phage lysin is linked to the C-terminal end of the human IgG1 Fc. The cysteine in the hinge region of the IgG1 will form S-S bonds to produce a stable homodimer.
B. How the lysibody is constructed: A promotor followed by the leader sequence (L) and a his tag (6H) for ease in purification. This is followed by the hinge region of human IgG 1 and human IgG1 Fc. After a short linker, the binding domain of a phage lysin in linked at the C-terminal end of the lysibody molecule. |
Date | |
Source | Own work |
Author | Vaf222 |
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current | 19:50, 21 January 2019 | 3,119 × 915 (84 KB) | Vaf222 (talk | contribs) | Cross-wiki upload from en.wikipedia.org |
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21 January 2019
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0fb635757fd7d51899663253400b5e9b3d23817e
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