File:Cadherin-2-Controls-Directional-Chain-Migration-of-Cerebellar-Granule-Neurons-pbio.1000240.s016.ogv
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Cadherin-2-Controls-Directional-Chain-Migration-of-Cerebellar-Granule-Neurons-pbio.1000240.s016.ogv (Ogg Theora video file, length 1 min 8 s, 320 × 240 pixels, 20 kbps, file size: 166 KB)
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[edit]DescriptionCadherin-2-Controls-Directional-Chain-Migration-of-Cerebellar-Granule-Neurons-pbio.1000240.s016.ogv |
English: This movie shows the dynamics of Cadherin-2 clusters in migrating GCs visualized by the expression of a Cadherin-2 reporter molecule (8xHSE:Cdh2Δ2-4ΔC-mCherry). During elongation, Cadherin-2 clusters (white arrowhead) accumulate in the leading edge, while they diminish from the rear compartment (yellow arrowhead). As the GC moves forward Cadherin-2 clusters concentrate along the lateral cell wall in close apposition to the neighboring GFP-expressing GC. Eventually during a resting phase, Cadherin-2 clusters can be found in the rear compartment again (overlay of GFP is shown in the second part of the movie). |
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Source | Video S14 from Rieger S, Senghaas N, Walch A, Köster R (2009). "Cadherin-2 Controls Directional Chain Migration of Cerebellar Granule Neurons". PLOS Biology. DOI:10.1371/journal.pbio.1000240. PMID 19901980. PMC: 2766073. | ||
Author | Rieger S, Senghaas N, Walch A, Köster R | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 22:17, 14 November 2012 | 1 min 8 s, 320 × 240 (166 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | This movie shows the dynamics of Cadherin-2 clusters in migrating GCs visualized by the expression of a Cadherin-2 reporter molecule (8xHSE:Cdh2?2-4?C-mCherry). During elongation, Cadherin-2 clusters (white arrowhead) accumulate in the leading edge, while they diminish from the rear compartment (yellow arrowhead). As the GC moves forward Cadherin-2 clusters concentrate along the lateral cell wall in close apposition to the neighboring GFP-expressing GC. Eventually during a resting phase, Cadherin-2 clusters can be found in the rear compartment again (overlay of GFP is shown in the second part of the movie). |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009-11 |