File:Continuum-Molecular-Simulation-of-Large-Conformational-Changes-during-Ion–Channel-Gating-pone.0020186.s006.ogv
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[edit]DescriptionContinuum-Molecular-Simulation-of-Large-Conformational-Changes-during-Ion–Channel-Gating-pone.0020186.s006.ogv |
English: Probability distribution of subunits in configuration space during gating, when the membrane potential decreased to −100 mV from an activated potential of +60 mV. Vertical dashed line is the assumed border between resting and activated conformations. The white vertical curve shows the flux within configuration space across this border. The net flux from the open state to the permissive state is shown by the arrow exiting the open state toward the subunit configuration space at the top right corner. Open state probability is shown (color scale) in the square on the upper right and plotted as a function of time in the right bottom panel. |
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Source | Movie S2 from Nekouzadeh A, Rudy Y (2011). "Continuum Molecular Simulation of Large Conformational Changes during Ion–Channel Gating". PLOS ONE. DOI:10.1371/journal.pone.0020186. PMID 21625456. PMC: 3098872. | ||
Author | Nekouzadeh A, Rudy Y | ||
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current | 13:22, 18 November 2012 | 28 s, 1,280 × 720 (1.18 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Nekouzadeh A, Rudy Y |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Probability distribution of subunits in configuration space during gating, when the membrane potential decreased to ?100 mV from an activated potential of +60 mV. Vertical dashed line is the assumed border between resting and activated conformations. The white vertical curve shows the flux within configuration space across this border. The net flux from the open state to the permissive state is shown by the arrow exiting the open state toward the subunit configuration space at the top right corner. Open state probability is shown (color scale) in the square on the upper right and plotted as a function of time in the right bottom panel. |
Software used | |
Date and time of digitizing | 2011 |
Language | English |