File:From mesenchymal stem cells to specific connective tissue cell types.png

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Description From mesenchymal stem cells to specific connective tissue cell types. Undifferentiated mesoderm-derived cells or mesenchymal stem cells are able to differentiate into different types of connective tissues including, bone, cartilage, tendon, and irregular connective tissue. Specific transcription factors have been identified as able to induce mesenchymal stem cell differentiation toward the different types of connective tissue cells. The Sox5/6/9, Runx2/Osx, Scx/Mkx/Egr1, and Tcf4/Tbx5/Osr1 genes drive undifferentiated cells to differentiate into cartilage, bone, tendon and irregular connective tissue, respectively.
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Source https://www.researchgate.net/publication/315526863_Non-myogenic_Contribution_to_Muscle_Development_and_Homeostasis_The_Role_of_Connective_Tissues Non-myogenic Contribution to Muscle Development and Homeostasis: The Role of Connective Tissues. Front. Cell Dev. Biol. 5:22. doi: 10.3389/fcell.2017.00022
Author Nassari S, Duprez D and Fournier-Thibault C
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Copyright © 2017 Nassari, Duprez and Fournier-Thibault. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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current20:33, 9 May 2024Thumbnail for version as of 20:33, 9 May 20241,085 × 877 (337 KB)Rasbak (talk | contribs){{Information |description= From mesenchymal stem cells to specific connective tissue cell types. Undifferentiated mesoderm-derived cells or mesenchymal stem cells are able to differentiate into different types of connective tissues including, bone, cartilage, tendon, and irregular connective tissue. Specific transcription factors have been identified as able to induce mesenchymal stem cell differentiation toward the different types of connective tissue cells. The Sox5/6/9, Runx2/Osx, Scx/Mkx...

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